Cofactor Genomics is a biotech company focused on RNA-based predictive diagnostics and precision medicine. It develops clinical assays, including tests aimed at predicting response to immunotherapy in cancer patients.
Access to pre-IPO shares is available to accredited investors through UpMarket.
Latest Price
Previous Price
Series B - II Aug 2023
How to Invest in Cofactor Genomics Through UpMarket
Cofactor Genomics shares are not on public exchanges. UpMarket provides accredited investors access through secondary market transactions.
Step 01
Verify accredited investor status
Confirm eligibility under SEC Rule 501 of Regulation D. Income or net worth threshold applies.
Step 02
Create an UpMarket account
Complete KYC/AML onboarding. Typically 1–2 business days. Licensed rep assigned on signup.
Step 03
Review available Cofactor Genomics offerings
Full offering memoranda and risk disclosures provided before any commitment is required.
Step 04
Complete subscription documents
Review and sign subscription agreement. All documents handled digitally through the platform.
Step 05
Fund your investment
Wire transfer or ACH. $50K minimum. Funds held in custodial account until close.
Pre-IPO investments are illiquid, speculative, and involve risk of total loss of capital.
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Valuation Growth Over Time
Post-money valuation by round
Previous roundsMost recent
Date
Round
PPS (split-adj.)
Valuation
Dec 2025
Series B - III
Aug 2023
Series B - II
Cofactor Genomics Revenue and Growth
Annual revenue
Why Investors Are Watching Cofactor Genomics
Growth Signal
OncoPrism launched in NSCLC after Medicare coverage in HNSCC
Cofactor said OncoPrism-HNSCC received Medicare coverage in late 2024, then expanded into OncoPrism-NSCLC after national clinical validation. The company says commercialization is ramping in two indicated cancers while PREDAPT continues across 11 solid tumor cancers.
Competitive Moat
2T data points and 10,000+ samples back Health Expression Models
Cofactor says it invested over $10M over a decade to build the world’s largest database of Health Expression Models. The platform is trained on 2 trillion data points from more than 10,000 patient samples, creating a proprietary RNA data moat.
Market Opportunity
Company targets $1.7B annual TAM across high-need cancer subtypes
Cofactor says it is prioritizing cancer subtypes with the highest unmet clinical need and estimates a $1.7B annual TAM. The company also cites more than 2,400 annual cancer-immunotherapy drug clinical trials as a large addressable market for predictive diagnostics.
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No. As of March 2026, Cofactor Genomics is a private company and does not trade on any public stock exchange. Accredited investors can access Cofactor Genomics shares through UpMarket, a FINRA-registered broker-dealer that specializes in pre-IPO investments.
Cofactor Genomics does not have a public stock price because it is privately held. The most recent known share price comes from its last funding round. Pre-IPO share prices on the secondary market may differ from the last round price depending on supply, demand, and market conditions.
Yes. Accredited investors can indicate interest in Cofactor Genomics shares through UpMarket by filling out the form on this page or creating an account at upmarket.co. All pre-IPO offerings are subject to availability and require a $50,000 minimum investment. UpMarket is a FINRA-registered broker-dealer and has brokered more than $500M in alternative investments since 2019.
Pre-IPO investments carry significant risks. Cofactor Genomics shares are illiquid, meaning there is no public market to sell them quickly. There is no guaranteed exit timeline or return. The investment is speculative in nature, and investors should be prepared for the possibility of total loss. Valuations of private companies can fluctuate substantially between funding rounds. Investors should consult their financial advisor and review all offering documents before investing.
In a pre-IPO transaction, accredited investors purchase shares from existing shareholders (such as employees, early investors, or other holders) through secondary market platforms. The company itself does not issue new shares in these transactions. UpMarket facilitates these trades as a FINRA-registered broker-dealer, handling compliance, documentation, and settlement on behalf of both parties.
There are two primary exit paths for pre-IPO holdings: selling your shares on the secondary market to another buyer, or holding until the company completes an IPO or is acquired. Both paths are subject to transfer restrictions, company approval (right of first refusal), and market conditions. The timing of any exit is unpredictable, and investors should plan for a multi-year holding period.
The minimum investment for most pre-IPO offerings on UpMarket is $50,000. This amount may vary depending on the specific offering and share availability. There are no fees to create an UpMarket account or browse available investments. Investors only pay transaction-related fees when they complete an investment.
UpMarket's valuation estimate of is derived from a proprietary model that incorporates multiple data sources: funding round data (Caplight), revenue estimates (Sacra), secondary market pricing, and public company comparables. The model applies a private company discount to the public comp multiple to account for illiquidity and information asymmetry. This estimate is not investment advice and may differ substantially from the price at which shares actually trade.
Cofactor Genomics generated $6M in 2024 revenue and develops RNA-based predictive diagnostics and precision medicine assays, with OncoPrism launched in NSCLC after Medicare coverage in HNSCC — accredited investors can access Cofactor Genomics stock through UpMarket.